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ImmunoWay Biotechnology Company
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Abbexa Ltd
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Novatein Inc
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ELK Biotechnology
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USCNK Inc
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Image Search Results
Journal: Theranostics
Article Title: Major vault protein (MVP) negatively regulates osteoclastogenesis via calcineurin-NFATc1 pathway inhibition
doi: 10.7150/thno.58468
Figure Lengend Snippet: Specific deletion of MVP in osteoclast precursors also induces an osteoporosis phenotype in mice. (A) Image of femurs in Lyz2-Cre (Cre), Mvp f/f (f/f) and Mvp f/f Lyz2-Cre (f/f/△) mice aged 3, 8, and 24 weeks, as assessed by micro-CT. Scale bar: 1 mm. (B) 3D microstructural analysis of femurs from 8 and 24-week-old mice. Scale bar: 500 µm. (C) Quantitative analysis of femurs in (B); BV/TV, bone volume/tissue volume; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular separation; Ct.Th, cortical thickness. (D) H&E staining of femurs from f/f and f/f/△ mice aged 8 weeks. Scale bar: 400 µm. (E) Quantification of H&E staining in (D). (F) Mineral apposition marked by calcitriol and alizarin red in two groups. Scale bar: 5 µm. (G) Quantitative analysis of relative MAR in (F). MAR, mineral apposition rate. (H) ELISA detection of PINP (serum bone-formation marker) from 8-week-old mice serum. (I) ELISA detection of CTX-1 (serum bone-resorption marker) from 8-week-old mice serum. (J) TRAP staining of femurs from 8-week-old mice. Scale bar: 50 µm. (K) Quantitative analysis of osteoclasts in (J). Oc.S/BS, osteoclast surface/bone surface; N.Oc/B.Pm, osteoclast number/bone perimeter. All experiments were repeated three times. *p < 0.05; **p < 0.01; ns, not significant, as determined by Student's t-test.
Article Snippet: Rates of bone resorption and formation in the serum of eight-week-old mice were determined using C-telopeptide of type I collagen (CTX-1) ELISA (Cusabio) and
Techniques: Micro-CT, Staining, Enzyme-linked Immunosorbent Assay, Marker
Journal: Biomedicines
Article Title: High-Dose Intravenous Steroid Treatment Seems to Have No Long-Term Negative Effect on Bone Mineral Density of Young and Newly Diagnosed Multiple Sclerosis Patients: A Pilot Study
doi: 10.3390/biomedicines11020603
Figure Lengend Snippet: Patients’ characteristics at baseline and after 24-months follow-up.
Article Snippet: N-terminal-propeptide-procollagen-type-1 (P1NP) was measured by
Techniques: